CC2D1A explained

Coiled-coil and C2 domain-containing protein 1A is a protein that in humans is encoded by the CC2D1A gene.^{[1] [2] [3]}

Further reading

• Albert PR, Lemonde S . 5-HT1A receptors, gene repression, and depression: guilt by association . The Neuroscientist . 10 . 6 . 575–93 . 2005 . 15534042 . 10.1177/1073858404267382 . 30402944 .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Basel-Vanagaite L . Mapping of a new locus for autosomal recessive non-syndromic mental retardation in the chromosomal region 19p13.12-p13.2: further genetic heterogeneity . J. Med. Genet. . 40 . 10 . 729–32 . 2003 . 14569116 . 10.1136/jmg.40.10.729 . 1735276 . Alkelai A . Straussberg R . 3 . Magal . N . Inbar . D . Mahajna . M . Shohat . M .
• Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . Suzuki Y . Nishikawa T . 3 . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
• Lemonde S, Rogaeva A, Albert PR . Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene . J. Neurochem. . 88 . 4 . 857–68 . 2004 . 14756806 . 10.1046/j.1471-4159.2003.02223.x . 37176837 . free .
• Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Rush J . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . Moritz A . Lee KA . 3 . Guo . Ailan . Goss . Valerie L . Spek . Erik J . Zhang . Hui . Zha . Xiang-Ming . Polakiewicz . Roberto D . 7200157 .
• Beausoleil SA . A probability-based approach for high-throughput protein phosphorylation analysis and site localization . Nat. Biotechnol. . 24 . 10 . 1285–92 . 2006 . 16964243 . 10.1038/nbt1240 . Villén J . Gerber SA . 3 . Rush . John . Gygi . Steven P . 14294292 .
• Rogaeva A . Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene . J. Biol. Chem. . 282 . 29 . 20897–905 . 2007 . 17535813 . 10.1074/jbc.M610038200 . Ou XM . Jafar-Nejad H . 3 . Lemonde . S. . Albert . P. R. . free .
• Rogaeva A, Albert PR . The mental retardation gene CC2D1A/Freud-1 encodes a long isoform that binds conserved DNA elements to repress gene transcription . Eur. J. Neurosci. . 26 . 4 . 965–74 . 2007 . 17714190 . 10.1111/j.1460-9568.2007.05727.x . 29590846 .

Notes and References

1. Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S . Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways . Oncogene . 22 . 21 . 3307–18 . May 2003 . 12761501 . 10.1038/sj.onc.1206406 . free .
2. Basel-Vanagaite L, Attia R, Yahav M, Ferland RJ, Anteki L, Walsh CA, Olender T, Straussberg R, Magal N, Taub E, Drasinover V, Alkelai A, Bercovich D, Rechavi G, Simon AJ, Shohat M . The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation . J Med Genet . 43 . 3 . 203–10 . Mar 2006 . 16033914 . 2563235 . 10.1136/jmg.2005.035709 .
3. Web site: Entrez Gene: CC2D1A coiled-coil and C2 domain containing 1A.