CC-preferring endodeoxyribonuclease explained

CC-preferring endodeoxyribonuclease
Ec Number:3.1.21.6
Cas Number:37211-67-9

CC-preferring endodeoxyribonuclease (Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC

This enzyme has preference for CC sites in double-stranded circular and linear DNA.

Notes and References

  1. A site-specific single-strand endonuclease activity induced by NYs-1 virus-infection of a Chlorella-like green-alga . Xia YN, Morgan R, Schildkraut I, Van Etten JL . Nucleic Acids Res. . 1988 . 16 . 9477–9487 . 3186439 . 10.1093/nar/16.20.9477 . 20 . 338757.
  2. A Streptomyces glaucescens endodeoxyribonuclease which shows a strong preference for CC dinucleotide . Aparicio JF, Freije JM, Lopez-Otin C, Cal S, Sanchez J . Eur. J. Biochem. . 1992 . 205 . 695–699 . 1533367 . 10.1111/j.1432-1033.1992.tb16831.x . 2. free .