CatSper4 explained

CatSper4, is a protein which in humans is encoded by the CATSPER4 gene.^{[1] [2] [3]} CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca²⁺-permeant ion channel specific essential for the correct function of sperm cells.^[4]

Notes and References

1. Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D . Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis . Reprod. Biol. Endocrinol. . 1 . 53 . August 2003 . 12932298 . 184451 . 10.1186/1477-7827-1-53 . free .
2. Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE . All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility . Proc. Natl. Acad. Sci. U.S.A. . 104 . 4 . 1219–23 . January 2007 . 17227845 . 1770895 . 10.1073/pnas.0610286104 . free .
3. Clapham DE, Garbers DL . International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels . Pharmacol. Rev. . 57 . 4 . 451–4 . December 2005 . 16382101 . 10.1124/pr.57.4.7 . 35096827 .
4. • Web site: CatSper and Two-Pore Channels: Introduction . IUPHAR Database of Receptors and Ion Channels . International Union of Basic and Clinical Pharmacology .