CACUL1 explained

CDK2 associated cullin domain 1 is a protein that in humans is encoded by the CACUL1 gene.^[1]

Further reading

• Kong Y, Nan K, Yin Y . Identification and characterization of CAC1 as a novel CDK2-associated cullin . Cell Cycle . 8 . 21 . 3552–61 . 2009 . 19829063 . 10.4161/cc.8.21.9955 . free .
• Kong Y, Bai PS, Sun H, Nan KJ . Expression of the newly identified gene CAC1 in the hippocampus of Alzheimer's disease patients . J. Mol. Neurosci. . 47 . 2 . 207–18 . 2012 . 22415352 . 10.1007/s12031-012-9717-5 . 14719772 .
• Kong Y, Bai PS, Sun H, Nan KJ, Chen NZ, Qi XG . The deoxycholic acid targets miRNA-dependent CAC1 gene expression in multidrug resistance of human colorectal cancer . Int. J. Biochem. Cell Biol. . 44 . 12 . 2321–32 . 2012 . 22903020 . 10.1016/j.biocel.2012.08.006 .
• Moon M, Um SJ, Kim EJ . CAC1 negatively regulates RARα activity through cooperation with HDAC . Biochem. Biophys. Res. Commun. . 427 . 1 . 41–6 . 2012 . 22982681 . 10.1016/j.bbrc.2012.08.142 .
• Kim J, Park UH, Moon M, Um SJ, Kim EJ . Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1 . FEBS Lett. . 587 . 1 . 17–22 . 2013 . 23178685 . 10.1016/j.febslet.2012.10.054 . 207659623 . free .
• Zheng Q, Zhao LY, Kong Y, Nan KJ, Yao Y, Liao ZJ . CDK-associated Cullin 1 can promote cell proliferation and inhibit cisplatin-induced apoptosis in the AGS gastric cancer cell line . World J Surg Oncol . 11 . 5 . 2013 . 23311997 . 3585504 . 10.1186/1477-7819-11-5 . free .
• Chen TJ, Gao F, Yang T, Thakur A, Ren H, Li Y, Zhang S, Wang T, Chen MW . CDK-associated Cullin 1 promotes cell proliferation with activation of ERK1/2 in human lung cancer A549 cells . Biochem. Biophys. Res. Commun. . 437 . 1 . 108–13 . 2013 . 23806693 . 10.1016/j.bbrc.2013.06.048 .
• Kong Y, Ma LQ, Bai PS, Da R, Sun H, Qi XG, Ma JQ, Zhao RM, Chen NZ, Nan KJ . Helicobacter pylori promotes invasion and metastasis of gastric cancer cells through activation of AP-1 and up-regulation of CACUL1 . Int. J. Biochem. Cell Biol. . 45 . 11 . 2666–78 . 2013 . 24004834 . 10.1016/j.biocel.2013.08.015 .
• Ma HL, Wen XP, Zhang XZ, Wang XL, Zhao DL, Che SM, Dang CX . miR-106a* inhibits the proliferation of esophageal carcinoma cells by targeting CDK2-associated Cullin 1 (CACUL1) . Cell. Mol. Biol. (Noisy-le-grand) . 61 . 4 . 56–62 . 2015 . 26314198 .

Notes and References

1. Web site: Entrez Gene: CDK2 associated cullin domain 1. 2018-01-05.