CACNB3 explained

Voltage-dependent L-type calcium channel subunit beta-3 is a protein that in humans is encoded by the CACNB3 gene.^{[1] [2]}

See also

• Voltage-dependent calcium channel

Further reading

• Yamada Y, Masuda K, Li Q . The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes. . Genomics . 27 . 2 . 312–9 . 1995 . 7557998 . 10.1006/geno.1995.1048 . etal.
• Rosenfeld MR, Wong E, Dalmau J . Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen. . Ann. Neurol. . 33 . 1 . 113–20 . 1993 . 8494331 . 10.1002/ana.410330126 . 24241609 . etal.
• Murakami M, Wissenbach U, Flockerzi V . Gene structure of the murine calcium channel beta3 subunit, cDNA and characterization of alternative splicing and transcription products. . Eur. J. Biochem. . 236 . 1 . 138–43 . 1996 . 8617257 . 10.1111/j.1432-1033.1996.t01-1-00138.x . free .
• Scott VE, De Waard M, Liu H . Beta subunit heterogeneity in N-type Ca2+ channels. . J. Biol. Chem. . 271 . 6 . 3207–12 . 1996 . 8621722 . 10.1074/jbc.271.6.3207 . etal. free .
• Bell DC, Butcher AJ, Berrow NS . Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents. . J. Neurophysiol. . 85 . 2 . 816–27 . 2001 . 11160515 . 10.1152/jn.2001.85.2.816. 147295966 . etal.
• Colecraft HM, Alseikhan B, Takahashi SX . Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells. . J. Physiol. . 541 . Pt 2 . 435–52 . 2002 . 12042350 . 10.1113/jphysiol.2002.018515 . 2290333 . etal.
• Murakami M, Fleischmann B, De Felipe C . Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels. . J. Biol. Chem. . 277 . 43 . 40342–51 . 2002 . 12161429 . 10.1074/jbc.M203425200 . etal. free . 10261/310195 . free .
• Qin N, Yagel S, Momplaisir ML . Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit. . Mol. Pharmacol. . 62 . 3 . 485–96 . 2002 . 12181424 . 10.1124/mol.62.3.485 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . etal. free . 2002PNAS...9916899M .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Chen YH, Li MH, Zhang Y . Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels. . Nature . 429 . 6992 . 675–80 . 2004 . 15170217 . 10.1038/nature02641 . 2004Natur.429..675C . 4422712 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Vendel AC, Terry MD, Striegel AR . Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex. . J. Neurosci. . 26 . 10 . 2635–44 . 2006 . 16525042 . 10.1523/JNEUROSCI.0067-06.2006 . 6675161 . etal. free .

Notes and References

1. Collin T, Lory P, Taviaux S, Courtieu C, Guilbault P, Berta P, Nargeot J . Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit . Eur J Biochem . 220 . 1 . 257–62 . Apr 1994 . 8119293 . 10.1111/j.1432-1033.1994.tb18621.x .
2. Web site: Entrez Gene: CACNB3 calcium channel, voltage-dependent, beta 3 subunit.