CACNA1I explained

Calcium channel, voltage-dependent, T type, alpha 1I subunit, also known as CACNA1I or Cav3.3 is a protein which in humans is encoded by the CACNA1I gene.[1] [2] [3]

Function

Voltage-dependent calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.[1]

See also

Notes and References

  1. Web site: Entrez Gene: CACNA1H calcium channel, voltage-dependent, T type, alpha 1I subunit.
  2. Mittman S, Guo J, Emerick MC, Agnew WS . Structure and alternative splicing of the gene encoding alpha1I, a human brain T calcium channel alpha1 subunit . Neurosci. Lett. . 269 . 3 . 121–4 . July 1999 . 10454147 . 10.1016/S0304-3940(99)00319-5 . 140208155 . free .
  3. Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J . International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels . Pharmacol. Rev. . 57 . 4 . 411–25 . December 2005 . 16382099 . 10.1124/pr.57.4.5 . 10386627 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "CACNA1I".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.