| Côme-Séraphin Cherrier | |
| Office: | Member of the Legislative Assembly of Quebec for Laprairie |
| Predecessor: | Cyrille Doyon |
| Successor: | Esioff-Léon Patenaude |
| Term Start: | 1897 |
| Term End: | 1908 |
| Birth Date: | 4 April 1848 |
| Birth Place: | Sainte-Philomène-de-Châteauguay (today Mercier), Canada East |
| Death Place: | La Prairie, Quebec |
| Party: | Liberal |
Côme-Séraphin Cherrier (4 April 1848 - 29 November 1912) was a member of the Legislative Assembly of Quebec.
He was first elected to the Legislative Assembly in the 1897 Quebec general election for the Quebec Liberal Party in Laprairie electoral district. He was re-elected in 1900 and 1904, but was defeated in 1908.