Butyltolylquinuclidine Explained

2-Butyl-3-(p-tolyl)quinuclidine (BTQ) is a stimulant DRI.^[1] It is one of a number of substituted quinuclidine derivatives developed as potential medications for the treatment of cocaine abuse,^[2] and produces similar effects to cocaine in animal studies, although milder and longer-lasting.

See also

• AL-1095

Notes and References

1. Sakamuri S, Enyedy IJ, Zaman WA, Tella SR, Kozikowski AP, Flippen-Anderson JL, Farkas T, Johnson KM, Wang S . 6 . 2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors . Bioorganic & Medicinal Chemistry . 11 . 6 . 1123–36 . March 2003 . 12614900 . 10.1016/S0968-0896(02)00450-9 .
2. Enyedy IJ, Sakamuri S, Zaman WA, Johnson KM, Wang S . Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors . Bioorganic & Medicinal Chemistry Letters . 13 . 3 . 513–7 . February 2003 . 12565962 . 10.1016/S0960-894X(02)00943-5 .