| Buffalo Presbyterian Church and Cemeteries | |
| Location: | 1333 Carthage St., Sanford, North Carolina |
| Coordinates: | 35.4611°N -79.1936°W |
| Built: | , 1926 |
| Architect: | J.J. Minor |
| Builder: | John B. Masemore |
| Architecture: | Gothic Revival, Colonial Revival |
| Added: | February 5, 1999 |
| Refnum: | 99000090 |
Buffalo Presbyterian Church and Cemeteries is a historic Presbyterian church and cemeteries located at 1333 Carthage Street in Sanford, Lee County, North Carolina. It was built in 1879, and is a two-story, gable-fronted, Gothic Revival style frame building. The front facade features lancet-arched double-leaf entries, lancet-arched windows, and a three-stage projecting entry tower with a flared, pyramidal roof and finial. Associated with the church is the manse built in 1926. It is a two-story, hip-roofed frame dwelling with Colonial Revival detailing. Also on the property are the original church cemetery, a cemetery for African-American congregants, the Matthews family plot, and the main cemetery.[1] It is the oldest Presbyterian Church in Lee County, Sanford, North Carolina.[2] This is an active congregation of the Presbyterian Church USA.
It was listed on the National Register of Historic Places in 1999.