| Official Name: | Buffalo, Humphreys County, Tennessee |
| Settlement Type: | Unincorporated community |
| Pushpin Map: | Tennessee#USA |
| Pushpin Label: | Buffalo |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Tennessee |
| Subdivision Type2: | County |
| Subdivision Name2: | Humphreys |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 453 |
| Coordinates: | 35.8856°N -87.8067°W |
| Area Code: | 931 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 1314764 |
Buffalo is an unincorporated community in Humphreys County, Tennessee, United States. The business part of the community is located on State Route 13 where it crosses Interstate 40. The older rural location was about a mile northwest of the current business area. It also a part of Hurricane Mills' zip code, 37078.