| Official Name: | Buffalo, Ohio |
| Settlement Type: | Census-designated place |
| Pushpin Map: | Ohio#USA |
| Pushpin Label: | Buffalo |
| Pushpin Label Position: | top |
| Coordinates: | 39.9169°N -81.5206°W |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Type2: | County |
| Subdivision Type3: | Township |
| Subdivision Name1: | Ohio |
| Subdivision Name2: | Guernsey |
| Subdivision Name3: | Valley |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 1.27 |
| Area Total Sq Mi: | 0.49 |
| Area Land Km2: | 1.27 |
| Area Land Sq Mi: | 0.49 |
| Area Water Km2: | 0.00 |
| Area Water Sq Mi: | 0.00 |
| Elevation Ft: | 846 |
| Population Total: | 373 |
| Population As Of: | 2020 |
| Population Density Km2: | 293.84 |
| Population Density Sq Mi: | 761.22 |
| Postal Code Type: | ZIP code |
| Postal Code: | 43722 |
| Area Code: | 740 |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Blank Name: | FIPS code |
| Blank Info: | 39-10128[2] |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 2628869 |
Buffalo is an unincorporated community and census-designated place in eastern Valley Township, Guernsey County, Ohio, United States. As of the 2020 census it had a population of 373. It has a post office with the ZIP code 43722.[3] It lies along State Route 313.
Buffalo was originally called "Hartford", and under the latter name was platted in 1836.[4] A post office called Buffalo has been in operation since 1839.[5]