Buckeye Creek is a stream in northern Cape Girardeau County in the U.S. state of Missouri. It is a tributary of Apple Creek.
The stream headwaters arise just west of I-55 and south of Missouri Route E approximately two miles east of Oak Ridge (at 37.4972°N -89.6914°W) at an elevation of 600 feet.[1] The stream flows north to northeast passing under I-55 and U.S. Route 61 west of Shawneetown. Its confluence with Apple Creek is approximately two miles east of Old Appleton (at 37.5833°N -89.6719°W) at an elevation of 361 feet.[2]
Buckeye Creek was named for the buckeye trees lining its course.[3]