Bryan Grenfell Explained

Bryan Grenfell
Birth Name:Bryan Thomas Grenfell
Birth Date:7 December 1954
Field:Epidemiology
Workplaces:
Thesis Title:Population dynamics of baleen whales and krill in the Southern Ocean
Thesis Url:http://yorsearch.york.ac.uk/44YORK:44YORK_ALMA_DS21202451780001381
Thesis Year:1981

Bryan Thomas Grenfell (born 1954) is a British population biologist and the Kathryn Briger and Sarah Fenton Professor of Ecology and Evolutionary Biology and Public Affairs at the Princeton School of Public and International Affairs at Princeton University.[1]

Education

Grenfell earned a Bachelor of Science degree with honours from Imperial College London, and DPhil in biology from the University of York in 1981.[2]

Career and research

After his DPhil, Grenfell spent a post-doctoral period at Imperial College London, with Roy Anderson, before joining the faculty at the University of Sheffield. He moved to the University of Cambridge in 1990, to the Pennsylvania State University in 2004, and then to Princeton University in 2009. He has served as a member of the Board of Governors of the Wellcome Trust (2014–2021).[3] [4]

Grenfell's research focuses on the (often non-linear) dynamics and control of infectious diseases in humans and animals.[5] [6] He has used simple epidemiological models and time series analysis to interpret large spatio-temporal datasets, elucidating the spread through time and space of acute infectious pathogens, notably measles.[7] [8]

In 2004, Grenfell and colleagues coined the term phylodynamics to describe the interaction between pathogen evolutionary dynamics and the dynamics of epidemics.[9] This concept has been widely applied since, for example, in discussing how pathogens evolve in response to host immunity.[10]

Grenfell and collaborators have been extensively involved in analyzing the dynamics of the Severe Acute Respiratory Syndrome Coronavirus 2 pandemic that began in 2020. In particular, they have focused on the impact of immune life history on the future dynamics of the pandemic and the performance of vaccination strategies.[11] [12]

Awards and honours

In 1991 Grenfell was awarded a T.H. Huxley Medal from Imperial College London, and in 1995 the 1995 Scientific Medal of the Zoological Society of London. He was elected a Fellow of the Royal Society (FRS) in 2004.[13] He has been a member of the American Academy of Arts and Sciences since 2006, and a Fellow of the American Association for the Advancement of Science since 2011. In 2008, he was awarded an Honorary Doctorate by the University of Sheffield. In 2022 he received the Kyoto Prize in Basic Sciences.[14]

Notes and References

  1. https://www.princeton.edu/eeb/people/display_person.xml?netid=grenfell&display=All Bryan Grenfell
  2. http://science.psu.edu/journal/Summer2005/NewFacSum05.htm Bryan Grenfell, Alumni Professor of the Biological Sciences
  3. https://wellcome.ac.uk/press-release/professor-bryan-grenfell-and-professor-tobias-bonhoeffer-join-wellcome-trust-board Professor Bryan Grenfell and Professor Tobias Bonhoeffer join the Wellcome Trust Board of Governors
  4. Web site: https://web.archive.org/web/20160622102531/https://wellcome.ac.uk/about-us/governance/board-governors. 2016-06-22. Board of Governors. Wellcome Trust. wellcome.ac.uk. London. Anon. 2016.
  5. Grenfell, Bryan T., and Andrew P. Dobson (eds). Ecology of infectious diseases in natural populations. Vol. 7. Cambridge University Press, 1995.
  6. 10.1016/S0140-6736(16)30164-7. Use of serological surveys to generate key insights into the changing global landscape of infectious disease. 2016. Metcalf. C. Jessica E.. Farrar. Jeremy. Jeremy Farrar. Cutts. Felicity T.. Basta. Nicole E.. Graham. Andrea L.. Andrea L. Graham. Lessler. Justin. Ferguson. Neil M.. Neil Ferguson (epidemiologist). Burke. Donald S.. Donald Burke. Grenfell. Bryan T.. Bryan Grenfell. The Lancet. 388. 10045. 728–730. 27059886. 5678936.
  7. 10.1038/414716a. Travelling waves and spatial hierarchies in measles epidemics. 2001. Grenfell. BT. Kappey. J. Bjornstad. ON. Nature. 414. 6865. 716–723. 11742391. 2805 .
  8. Grenfell, Bryan T.Measles: Nonlinearity and Stochasticity in an Epidemic Metapopulation, Oxford University Press, 2008,
  9. Grenfell. B. T.. Unifying the Epidemiological and Evolutionary Dynamics of Pathogens. Science. 303. 5656. 2004. 327–332. 0036-8075. 10.1126/science.1090727. 14726583. Oliver . Pybus. Oliver Pybus. Julia . Gog. Julia Gog. James . Wood. Janet . Daly. Jenny. Mumford. Edward C.. Holmes. 2004Sci...303..327G . 4017704 . Edward C. Holmes.
  10. Voltz . Eric M. Katia. Koelle. Julia. Gog. Julia Gog. Viral Phylodynamics . PLOS Computational Biology . 2013 . 9 . 3 . e1002947. 10.1371/journal.pcbi.1002947 . 23555203 . 3605911 . 2013PLSCB...9E2947V . free .
  11. 10.1126/science.abd7343. Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 years. 2020 . Saad-Roy. Chadi . et al.. Science . 370 . 6518 . 811–818. 32958581. 7857410. 2020Sci...370..811S.
  12. 10.1126/science.abj7364. Vaccine nationalism and the dynamics and control of SARS-CoV-2. 2021 . Wagner. Caroline . et al. . Science . 373 . 6562 . eabj7364. 34404735 . 9835930. 237199024.
  13. Web site: https://web.archive.org/web/20151117112504/https://royalsociety.org/people/bryan-grenfell-11531/ . 2015-11-17 . Professor Bryan Grenfell OBE FRS . . London . royalsociety.org . Anon . 2015 . One or more of the preceding sentences incorporates text from the royalsociety.org website where:
  14. https://www.kyotoprize.org/en/laureates/bryan_t_grenfell/ Kyoto Prize 2022