Brunfelsia uniflora (syn. Brunfelsia hopeana), the manac, is a species of flowering plant in the family Solanaceae.[1] It is native to Monos island of Trinidad and Tobago, Venezuela, the Venezuelan Antilles, Guyana, Brazil, and northwest Argentina, and has been introduced to eastern Tropical Africa, Réunion, Mauritius, India, and Assam.[2] A poisonous evergreen shrub typically tall, it is commonly cultivated as an ornamental, and as an ingredient in ayahuasca and other potions, usually under its synonym Brunfelsia hopeana.[3] [4]