Brunó Ferenc Straub Explained

Brunó Ferenc Straub
Nationality:Hungarian
Order:Chairman of the Presidential Council of the People's Republic of Hungary
Term Start:29 June 1988
Term End:23 October 1989
1Blankname:Chairman of the Council of Ministers
1Namedata:Károly Grósz
Miklós Németh
Predecessor:Károly Németh
Successor:Mátyás Szűrös
Birth Date:5 January 1914
Birth Place:Nagyvárad, Austria-Hungary (now Oradea, Romania)
Death Place:Budapest
Party:Hungarian Socialist Workers Party
Spouse:Erzsébet Lichneckert (1940–1967)
Gertrud Szabolcsi (1972–1993)
Children:2 daughters

Brunó Ferenc Straub (5 January 1914 in Nagyvárad, Austria-Hungary (now Oradea, Romania)  - 15 February 1996) was a biochemist. As a young scholar he was a research assistant of Albert Szent-Györgyi at the University of Szeged, and subsequently worked at the Molteno Institute, Cambridge, UK. He was the first to obtain actin in a relatively pure state.[1] He founded the Biological Research Centre in Szeged. He was the chairman of the Hungarian Presidential Council from 29 June 1988 to 23 October 1989. He proposed the theory of conformational selection in 1964,[2] [3] the same year the Monod–Wyman–Changeux model was proposed.[4] [5]

Notes and References

  1. Straub BF . 1942. Szent-Györgyi A . Actin. Studies from the Institute of Medical Chemistry University Szeged. 1942.. II. 3–15.
  2. 10.1016/j.tibs.2010.04.009 . Trends Biochem. Sci. . Csermely. P. . Palotai. R.. Nussinov. T.. 35 . 10 . Induced fit, conformational selection and independent dynamic segments: an extended view of binding events . 2010 . 539–546. 3018770 .
  3. 10.1007/s40656-021-00442-2. What’s in a name? From “fluctuation fit” to “conformational selection”: rediscovery of a concept. Orosz. F.. Vértessy. B. G.. Hist. Philos. Life Sci.. 2021. 43. 88. 8270835.
  4. Changeux. J.-P.. 1964. Allosteric interactions interpreted in terms of quaternary structure. Brookhaven Symp. Biol.. 17. 232–249. 14246265.
  5. Monod . J. Wyman . J . Changeux . J.-P.. 1965. On the Nature of Allosteric Transitions — a Plausible Model. J. Mol. Biol.. 12. 1. 88–118. 10.1016/S0022-2836(65)80285-6. 14343300.