Bronidox Explained

Bronidox, or 5-bromo-5-nitro-1,3-dioxane, is an antimicrobial chemical compound.

Bronidox causes inhibition of enzyme activity in bacteria.^[1]

Bronidox is corrosive to metals.^[2]

Uses

• Bactericide
• Fungicide, effective against yeast and other fungi
• It is used in immunology for preserving antibodies and antisera in 0.1 - 0.5% concentration. It is used as preservative to avoid use of sodium azide.
• Stabilizer
• Surfactant
• Used in cosmetics since the mid-1970s as preservative for shampoos, foam bath, etc. Maximum concentration is 0.1%.
• Some users do not recommend use in preparations destined for in vivo or tissue culture work^[3]

See also

• Bronopol

Notes and References

1. Ghannoum M, Thomson M, Bowman W, Al-Khalil S . Mode of action of the antimicrobial compound 5-bromo-5-nitro-1,3-dioxane (bronidox) . Folia Microbiol. (Praha) . 31 . 1 . 19–31 . 1986 . 3082729 . 10.1007/BF02928676 . 23920602.
2. http://www.products.cognis.com/COGNIS/prodleaf.nsf/(SBU_Catalog)/FFAD30C61B67EFEB41256B4100427DD1/$File/BRONIDOX_r_L_5_E.pdf
3. http://www.totalreproduction.com/products/specs/Bronidox.html