Brisavirus (isolate LC KY052047) is a species of Redondoviridae in the genus Torbevirus.[1] Brisa- is from the Spanish word for "Breeze", which refers to their isolation from the human respiratory tract. It was discovered in a throat swab in a male traveler who presented with fever, enlarged adenoids, flushed skin and myalgia after testing negative for other viruses.[2] Brisavirus like other viruses in the Redondoviridae family, are present and putatively replicate in the oro-respiratory tract.[3] They are associated in patients with critical illness and periodontitis.
Brisavirus has a CRESS DNA genome with 3 open reading frames that are inversely oriented that encode for the capsid and Replication-associated protein protein with a small and larger intergenic region.[4] They replicate using rolling-circle replication like other CRESS viruses. By using metagenomic analysis, researchers found that the encoded proteins were most similar to porcine stool-associated circular virus 5 isolate CP33 (PoSCV5).