| Brimstone Creek | |
| Pushpin Map: | New York Adirondack Park#USA |
| Pushpin Map Caption: | Location of the mouth within New York |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type3: | Region |
| Subdivision Name3: | Central New York Region |
| Subdivision Type4: | Counties |
| Subdivision Name4: | Schoharie, Montgomery |
| Subdivision Type5: | Towns |
| Subdivision Name5: | Sharon, Canajoharie |
| Source1 Location: | East of Sharon Springs |
| Source1 Coordinates: | 42.7964°N -74.5719°W |
| Mouth: | Canajoharie Creek |
| Mouth Location: | North-northwest of Ames |
| Mouth Coordinates: | 42.8467°N -74.6076°W[1] |
| Mouth Elevation: | 676feet |
| Basin Size: | 14.9mi2[2] |
Brimstone Creek is a river in Schoharie County and Montgomery County in New York. It begins east of the Village of Sharon Springs and flows mostly in a northwest direction before flowing into Canajoharie Creek north-northwest of the Village of Ames.