Brigitta Stockinger Explained

Gitta Stockinger
Birth Name:Brigitta Stockinger
Alma Mater:University of Mainz (PhD)

Brigitta Stockinger, FMedSci, FRS, is a molecular immunologist in the Francis Crick Institute in London. Stockinger's lab focus on understanding how certain immune cells, called T cells, develop and function as well as investigating how diet and other environmental factors can affect the way the immune system works.[1]

Stockinger focuses on a particular type of immune cell that helps to control immune responses to viruses, bacteria and other pathogens, called a CD4 T cell.

Stockinger's research has provided insights into a particular type of CD4 T cell, called a Th17 cell, looking at why some of these cells become inflammatory and cause damage in the body. Her lab identified a particular receptor, the aryl hydrocarbon receptor (AhR), which connects environmental stimuli and the immune system.[2] [3] [4] [5] [6] [7] [8] [9]

Education

Stockinger was educated at the University of Mainz, where she was awarded a PhD in Biology. She then did postdoctoral studies in London, Cambridge and at the Cancer Research Institute in Heidelberg.

Career

Awards and honours

Stockinger was elected a Fellow of the Royal Society in 2013. Her nomination reads:

In 2008, she was elected a member of European Molecular Biology Organization (EMBO). She is also a fellow of the Academy of Medical Sciences.

Notes and References

  1. Web site: Gitta Stockinger. 2020-09-16. Crick. en.
  2. 10.1038/nature06881. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature. 453. 7191. 106–109. 2008. Veldhoen . M. . Hirota . K. . Westendorf . A. M. . Buer . J. . Dumoutier . L. . Renauld . J. C. . Stockinger . B. . 18362914. 2008Natur.453..106V. 10033/30394. 205212907. free .
  3. 10.1038/ni.1659. 18931678. Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset. Nature Immunology. 9. 12. 1341–1346. 2008. Veldhoen . M. . Uyttenhove . C. . Van Snick . J. . Helmby . H. . Westendorf . A. . Buer . J. . Martin . B. . Wilhelm . C. . Stockinger . B. . 205361860.
  4. 16473830. 2006. Veldhoen. M. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 24. 2. 179–89. Hocking. R. J.. Atkins. C. J.. Locksley. R. M.. Stockinger. B. 10.1016/j.immuni.2006.01.001. free.
  5. 10.1186/1741-7007-11-115. 24279517. 3842812. Open questions: A few that need answers in immunology. BMC Biology. 11. 115. 2013. Stockinger . B. . free.
  6. 15128781. 2004. Vieira. P. L.. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. Journal of Immunology. 172. 10. 5986–93. Christensen. J. R.. Minaee. S. O'Neill. E. J.. Barrat. F. J.. Boonstra. A. Barthlott. T. Stockinger. B. Wraith. D. C.. O'Garra. A . 10.4049/jimmunol.172.10.5986. free.
  7. 10.1016/j.coi.2007.04.005. Differentiation and function of Th17 T cells. Current Opinion in Immunology. 19. 3. 281–6. 2007. Stockinger . B. . Veldhoen . M. . 17433650.
  8. 10.1038/nri3362. 23197111. The resolution of inflammation. Nature Reviews Immunology. 13. 1. 59–66. 2012. Buckley . C. D. . Gilroy . D. W. . Serhan . C. N. . Stockinger . B. . Tak . P. P. . 7549769.
  9. 8642293. 1996. Stockinger. B. B cells solicit their own help from T cells. The Journal of Experimental Medicine. 183. 3. 891–9. Zal. T. Zal. A. Gray. D. 2192359 . 10.1084/jem.183.3.891.
  10. Web site: Gitta Stockinger appointed Associate Research Director. 2020-09-16. Crick. en.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Brigitta Stockinger".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.