| Brian Sisley | |
| Number: | 93 |
| Position: | Defensive end |
| Birth Date: | 18 January 1964 |
| Birth Place: | Hot Springs, Arkansas, U.S. |
| Death Place: | St. Michael, Minnesota, U.S. |
| Height Ft: | 6 |
| Height In: | 4 |
| Weight Lb: | 235 |
| High School: | Edgemont |
| College: | South Dakota State |
| Undraftedyear: | 1987 |
| Pastteams: | |
| Pfr: | SislBr20 |
Brian D. Sisley (January 18, 1964 – January 31, 2013) was an American professional football defensive end. He played for the New York Giants in 1987 and appeared in three games.[1] One of the National Football League (NFL)'s replacement players during the players strike,[2] he had previously played college football for the South Dakota State Jackrabbits. He died in 2013, at the age of 49.[3]