| Brian Sharples | |
| Birth Date: | 6 September 1944 |
| Birth Place: | Bradford, England |
| Position: | Centre half |
| Youthyears1: | 1959–1961 |
| Youthclubs1: | Birmingham City |
| Years1: | 1961–1968 |
| Caps1: | 61 |
| Goals1: | 4 |
| Years2: | 1968–1971 |
| Caps2: | 68 |
| Goals2: | 4 |
Brian Sharples (born 6 September 1944) is an English former professional footballer born in Bradford who played as a centre half. He made 139 appearances in the Football League playing for Birmingham City and Exeter City.