| Brenne | |
| Map: | Brenne (rivière).png |
| Source1 Location: | Sombernon, Côte-d'Or |
| Source1 Coordinates: | 47.3139°N 4.71°W |
| Mouth Coordinates: | 47.6439°N 4.276°W |
| Subdivision Type1: | Country |
| Length: | 71.7km (44.6miles) |
The Brenne (pronounced as /fr/) is a 71.7km (44.6miles) river in Côte-d'Or in Bourgogne, eastern France. It rises in Sombernon and flows generally northwest to join the Armançon at Buffon, 6km (04miles) downstream from Montbard.