| Brendon Dedekind | |
| Birth Place: | Pietermaritzburg, KwaZulu-Natal, South Africa |
| Headercolor: | lightsteelblue |
| Show-Medals: | yes |
Brendon Dedekind (born 14 February 1976 in Pietermaritzburg, KwaZulu-Natal) is a South African retired swimmer. He won an international championship gold medal in the 50 m freestyle at the 1999 Pan Pacific Swimming Championships. Nicknamed Skinny Man, he competed in two consecutive Summer Olympics for his native country, starting in 1996, when he was a finalist in the 50 m freestyle.