| Brenda Mwika Tambatamba | |
| Office: | Minister of Labour and Social Security |
| Term Start: | 7 September 2021 |
| President: | Hakainde Hichilema |
| Office3: | Member of the National Assembly for Kasempa |
| Predecessor3: | Kabinga Pande |
| Term Start3: | August 2016 |
| Party: | United Party for National Development |
| Birth Date: | 1961 4, df=yes |
| Nationality: | Zambian |
| Predecessor: | Joyce Nonde-Simukoko |
| Occupation: | Politician |
Brenda Mwika Tambatamba (born 29 April 1961[1]) is a Zambian politician. She has been a member of the National Assembly of Zambia for Kasempa since 2016.[2] She is a member of the United Party for National Development. She is the current Minister of Labour and Social Security of Zambia.[3]