| Brandon Isaac | |
| Birth Date: | 1984 12, mf=yes |
| Birth Place: | Blackville, South Carolina, U.S. |
| Team: | Hamilton Tiger-Cats |
| Import: | yes |
| Position1: | Defensive backs |
| Height Ft: | 6 |
| Height In: | 3 |
| Weight Lb: | 208 |
| College: | South Carolina |
| Nfldraftedyear: | 2008 |
| Nfldraftedround: | Undrafted |
| Playing Years1: | 2008 |
| Playing Team1: | Spokane Shock |
| Playing Years2: | 2009 |
| Playing Team2: | Manchester Wolves |
| Playing Years3: | 2010* |
| Playing Team3: | Milwaukee Iron |
| Playing Years4: | – |
| Playing Team4: | Calgary Stampeders |
| Playing Years5: | – |
| Playing Team5: | Toronto Argonauts |
| Playing Team6: | Hamilton Tiger-Cats |
| Playing Team7: | Saskatchewan Roughriders |
| Playing Years8: | – |
| Playing Team8: | Toronto Argonauts |
| Coaching Team2: | Edmonton Elks (Defensive backs coach) |
| Coaching Team4: | Hamilton Tiger-Cats (Defensive backs coach) |
| Coaching Years4: | –present |
| Career Footnotes: | |
| Career Highlights: | |
| Cfl: | 4293 |
Brandon Isaac (born December 11, 1984) is the defensive backs coach for the Hamilton Tiger-Cats of the Canadian Football League (CFL). He is a former professional football linebacker. He has been a member of the Spokane Shock, Manchester Wolves, Milwaukee Iron, Calgary Stampeders, Hamilton Tiger-Cats, Saskatchewan Roughriders, and Toronto Argonauts. He is a Grey Cup champion, having won with the Argonauts in 2012.
Isaac played college football for the South Carolina Gamecocks. In his two-year tenure with the Gamecocks, Isaac recorded 55 tackles, one interception, and eight pass breakups.
Isaac was a member of the 100th Grey Cup winning Toronto Argonauts.
Fletcher served as the defensive backs coach for the Edmonton Elks from 2022 to 2023.
On February 2, 2024, it was announced that Isaac had joined the Hamilton Tiger-Cats to serve as the team's defensive backs coach.[1]