Branchpoint Binding Protein Explained

Branchpoint Binding Protein (BBP) is an Orem RNA processing factor. The protein complex binds to the branchpoint sequence (BPS) in the pre-mRNA, aiding in splice site recognition.[1]

The role of the protein in yeast cells has been the subject of study, as for other eukaryotic cells.[2] The BPS that the protein binds to in yeast is UACUAAC.[3]

References

  1. Web site: BBP Involved in Splice Site Recognition. https://web.archive.org/web/20100531150018/http://www.umbc.edu/bioclass/biol414/wiki/index.php?page=BBP_Involved_in_Splice_Site_Recognition. dead. 2010-05-31.
  2. The branchpoint binding protein: in and out of the spliceosome cycle. Adv Exp Med Biol. 10.1007/978-1-4419-7005-3_9. 21189690 . 693 . 2010 . 123–41. Rymond. B. C..
  3. The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC. 1997 . 10.1016/S0092-8674(00)80261-5 . Berglund . J.Andrew . Chua . Katrin . Abovich . Nadja . Reed . Robin . Rosbash . Michael . Cell . 89 . 5 . 781–787 . 9182766 . 10505875 . free .

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