| Event: | Boxing |
| Games: | 2010 South American Games |
| Prev: | 2006 |
| Next: | 2014 |
There were 14 boxing events at the 2010 South American Games: 11 men's events and 3 women's events. Competitions were held over March 22–27. All games were played at Sabaneta.
| Men's 48 kg | Arles Contreras | Carlos Quipo Pilataxi | Percy Pena Mori Eduard Bermúdez | |
| Men's 51 kg | Cei Ávila | Juliao Enriques Neto | Luis Caycho Dávila Fernando Martínez | |
| Men's 54 kg | Oscar Negrete | Alberto Melián | César Dahua Tuisima Yohandry Campos | |
| Men's 57 kg | Ángel Rodrígues | Deivis Julio Bassa | Luis Porozo Mina Ignacio Perrin | |
| Men's 60 kg | César Villarraga | Éverton Lopes | Erick Bone Banguera Juan Carrasco | |
| Men's 64 kg | Myke Carvalho | Miguel Escandón | Angelo Báez Aros Gustiniano Mina Caicedo | |
| Men's 69 kg | Brian Castaño | Leonard Carrillo | Esquiva Florentino Jonny Sánchez | |
| Men's 75 kg | Alfonso Blanco | Alex Theran | Jaime Cortés Padilla Yamaguchi Florentino | |
| Men's 81 kg | Carlos Góngora | Roaner Angulo | Yamil Peralta Washington Silva | |
| Men's 91 kg | Julio Castillo | Jeisson Monroy | Maximiliano Sosa Rafael Lima | |
| Men's +91 kg | José Payares | Jorge Quiñónes | Carlos Moreno Marcelo Cruz |
| Women's 51 kg | Érica Matos | Paola Benavídes | Ingrit Valencia Nupirat Kuja Wachapa |
| Women's 60 kg | Adriana Araujo | Daiana Sánchez | Jenifer Cáceres Moraily de Windt |
| Women's 75 kg | Andreia Bandeira | Celeste Peralta | |