| Botrugno | |
| Official Name: | Comune di Botrugno |
| Native Name: | Griko Greek, Modern (1453-);: Botruòduros |
| Shield Alt: | Coat of arms of Botrugno |
| Pushpin Label Position: | left |
| Coordinates: | 40.0667°N 37°W |
| Province: | (LE) |
| Area Total Km2: | 9 |
| Population Footnotes: | [1] |
| Population Total: | 2936 |
| Population As Of: | November 2008 |
| Population Demonym: | Botrugnesi |
| Elevation M: | 92 |
| Saint: | Saint Oronzo |
| Day: | 26 August |
| Postal Code: | 73020 |
| Area Code: | 0836 |
| Istat: | 075009 |
| Frazioni: | San Cassiano, Sanarica, Scorrano, Supersano |
Botrugno (Salentino: Sicilian: Vitrùgna) is a town and comune in the Italian province of Lecce in the Apulia region of south-east Italy.
The main sight is the marquisal palace, which was erected in 16th century and restored during the 17th century. It was Castriota Scanderbeg family in 1725 who built the baroque-style balcony.