| Official Name: | Bolshoye Yamkino |
| Native Name: | Большое Ямкино |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Velikoustyugsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 60.75°N 51°W[1] |
Bolshoye Yamkino (Russian: Большое Ямкино) is a rural locality (a village) in Mardengskoye Rural Settlement, Velikoustyugsky District, Vologda Oblast, Russia. The population was 1 as of 2002.[2]
Bolshoye Yamkino is located 16 km west of Veliky Ustyug (the district's administrative centre) by road. Polutino is the nearest rural locality.[3]