| Official Name: | Bolshoye Makarovo |
| Native Name: | Большое Макарово |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Mezhdurechensky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 59.3°N 45°W[1] |
Bolshoye Makarovo (Russian: Большое Макарово) is a rural locality (a village) in Sukhonskoye Rural Settlement, Mezhdurechensky District, Vologda Oblast, Russia. The population was 7 as of 2002.[2]
Bolshoye Makarovo is located 8 km southeast of Shuyskoye (the district's administrative centre) by road. Kalitino is the nearest rural locality.[3]