| Official Name: | Bolshepanyushevo |
| Native Name: | Большепанюшево |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Altai Krai#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Altai Krai |
| Subdivision Name3: | Aleysky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +7:00 |
| Coordinates: | 52.5°N 134°W[1] |
Bolshepanyushevo (Russian: Большепанюшево) is a rural locality (a selo) and the administrative center of Bolshepanyushevsky Selsoviet, Aleysky District, Altai Krai, Russia. The population was 507 as of 2013.[2] There are 9 streets.
Bolshepanyushevo is located on the Aley river, 8 km northeast of Aleysk (the district's administrative centre) by road. Uspenovka is the nearest rural locality.[3]