| Official Name: | Bolshaya Sinega |
| Native Name: | Большая Синега |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Velikoustyugsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 60.9167°N 75°W[1] |
Bolshaya Sinega (Russian: Большая Синега) is a rural locality (a village) in Krasavinskoye Rural Settlement, Velikoustyugsky District, Vologda Oblast, Russia. The population was 45 as of 2002.[2]
Bolshaya Sinega is located 23 km northeast of Veliky Ustyug (the district's administrative centre) by road. Vasilyevskoye is the nearest rural locality.[3]