| Official Name: | Boca del Río |
| Native Name Lang: | es |
| Settlement Type: | Town |
| Pushpin Map: | Venezuela |
| Pushpin Map Caption: | Location in Venezuela |
| Coordinates: | 10.9673°N -64.1811°W |
| Subdivision Type: | Country |
| Subdivision Type1: | State |
| Subdivision Name1: | Nueva Esparta |
Boca de Río is a town on Isla Margarita, in the state of Nueva Esparta, Venezuela. It is the capital of the Macanao Peninsula Municipality.