Blue River virus explained

Blue River virus (BRV) is a single-stranded, negative sense RNA virus of New World hantavirus isolated from a white-footed mouse (Peromyscus leucopus) near the Blue River in Jackson County, Missouri in 1995. Its genome is similar to Sin Nombre orthohantavirus (SNV) but varies in the S1 and S2 segments. Like Sin Nombre orthohantavirus, Blue River virus causes Hantavirus pulmonary syndrome (HPS) in humans.^{[1] [2] [3]}

Natural reservoir

As with all hantavirus species and their reservoirs, Blue River virus is unique to the white-footed mouse.^[4]

Transmission

As has been shown with other hantaviruses, transmission is through droplet respiration when rodent excreta becomes aerosolized. Blue River virus has not been shown to transfer via person-to-person.^{[4] [5]}

See also

• 1993 Four Corners hantavirus outbreak

External links

• "Hantaviruses, with emphasis on Four Corners Hantavirus" by Brian Hjelle, M.D., Department of Pathology, School of Medicine, University of New Mexico
• CDC's Hantavirus Technical Information Index page
• Viralzone: Hantavirus
• Virus Pathogen Database and Analysis Resource (ViPR): Hantaviridae
• Occurrences and deaths in North and South America
• Blue River virus genome

Notes and References

1. Orzunov, S.P., J.E.Rowe, T.G.Ksiazek, C.J. Peters, S.C.ST.Jeor, and S.T.Nichol.1998. Genetic analysis of the diversity and origin of hantaviruses in Peromyscus leucopus mice in NorthAmerica. J.Virology. 72:57–64.
2. [Charles Calisher|Charles H. Calisher]
3. Zaki SR, Greer PW, Coffield LM, Goldsmith CS, Nolte KB, Foucar K, Feddersen RM, Zumwalt RE, Miller GL, Khan AS, et al. Hantavirus pulmonary syndrome. Pathogenesis of an emerging infectious disease. Am J Pathol. 1995 Mar;146(3):552–579.
4. Klein SL, Calisher CH.Emergence and persistence of hantaviruses.Curr Top Microbiol Immunol. 2007;315:217–52.
5. Web site: CDC—How People Get Hantavirus Pulmonary Syndrome (HPS)—Hantavirus . Cdc.gov . 2012-08-29 . 2014-02-12.