Blood group B linear chain alpha-1,3-galactosidase explained

Baicalin-beta-D-glucuronidase
Ec Number:	3.2.1.167

Baicalin-beta-D-glucuronidase (baicalinase) is an enzyme with systematic name 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase.^{[1] [2] [3] [4]} This enzyme catalyses the following chemical reaction

baicalin + H₂O

\rightleftharpoons baicalein + D-glucuronate

The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency.

Notes and References

1. Ikegami F, Matsunae K, Hisamitsu M, Kurihara T, Yamamoto T, Murakoshi I . Purification and properties of a plant beta-D-glucuronidase form Scutellaria root . Biological & Pharmaceutical Bulletin . 18 . 11 . 1531–4 . November 1995 . 8593473 . 10.1248/bpb.18.1531 . free .
2. Purification and characterization of baicalin-β-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge . Zhang C, Zhang Y, Chen J, Liang X . Proc. Biochem. . 2005 . 40 . 1911–1915 . 10.1016/j.procbio.2004.07.003.
3. Sasaki K, Taura F, Shoyama Y, Morimoto S . Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi . The Journal of Biological Chemistry . 275 . 35 . 27466–72 . September 2000 . 10858442 . 10.1074/jbc.m004674200 . free .
4. Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi . Morimoto S, Harioka T, Shoyama Y . Planta . 1995 . 195 . 535–540 . 10.1007/bf00195712.