Blast2GO explained

Blast2GO
Image Alt:	Logo BioBam Bioinformatics
Type:	Bioinformatics Software
Company:	BioBam Bioinformatics
Models:	Demo, Basic, Trial, Pro, Plugin, Commandline
Url:	https://www.blast2go.com

Blast2GO, first published in 2005,^{[1] [2] [3] [4]} is a bioinformatics software tool for the automatic, high-throughput functional annotation of novel sequence data (genes proteins). It makes use of the BLAST^[5] algorithm to identify similar sequences to then transfers existing functional annotation from yet characterised sequences to the novel one. The functional information is represented via the Gene Ontology (GO), a controlled vocabulary of functional attributes. The Gene Ontology, or GO, is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species.^[6]

See also

• Protein function prediction
• Functional genomics
• Bioinformatics

Notes and References

1. Conesa. A. Götz, S . García-Gómez, JM . Terol, J . Talón, M . Robles, M . Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research.. Bioinformatics. Sep 15, 2005. 21. 18. 3674–6. 16081474. 10.1093/bioinformatics/bti610. free.
2. Götz. S. García-Gómez, JM . Terol, J . Williams, TD . Nagaraj, SH . Nueda, MJ . Robles, M . Talón, M . Dopazo, J . Conesa, A . High-throughput functional annotation and data mining with the Blast2GO suite. Nucleic Acids Research. June 2008. 36. 10. 3420–35. 18445632. 10.1093/nar/gkn176. 2425479.
3. Conesa. A. Götz, S. Blast2GO: A comprehensive suite for functional analysis in plant genomics. International Journal of Plant Genomics. 2008. 2008. 1–12. 18483572. 10.1155/2008/619832. 2375974. free.
4. Götz. S. Arnold, R . Sebastián-León, P . Martín-Rodríguez, S . Tischler, P . Jehl, MA . Dopazo, J . Rattei, T . Conesa, A . B2G-FAR, a species-centered GO annotation repository. Bioinformatics. Apr 1, 2011. 27. 7. 919–24. 21335611. 10.1093/bioinformatics/btr059. 3065692.
5. Altschul. SF. Gish, W . Miller, W . Myers, EW . Lipman, DJ . Basic local alignment search tool. Journal of Molecular Biology. Oct 5, 1990. 215. 3. 403–10. 2231712. 10.1016/S0022-2836(05)80360-2. 14441902 .
6. The Gene Ontology Consortium . The Gene Ontology project in 2008 . Nucleic Acids Res. . 36 . Database issue . D440–4 . January 2008 . 17984083 . 2238979 . 10.1093/nar/gkm883 .