| Jurisdiction: | Archdiocese |
| San Juan de Cuyo | |
| Latin: | Archidioecesis Sancti Ioannis de Cuyo |
| Local: | Arquidiócesis de San Juan de Cuyo |
| Country: | Argentina |
| Province: | San Juan de Cuyo |
| Area Km2: | 89,651 |
| Population: | 664,000 |
| Population As Of: | 2010 |
| Catholics: | 608,000 |
| Catholics Percent: | 91.6 |
| Parishes: | 41 |
| Denomination: | Roman Catholic |
| Rite: | Roman Rite |
| Established: | 1826 (years ago) |
| Cathedral: | San Juan de Cuyo Cathedral |
| Patron: | St John the Baptist St Clement I |
| Metro Archbishop: | Alfonso Delgado Evers |
| Bishop Title: | Archbishop |
| Website: | Website of the Archdiocese |
The Roman Catholic Archdiocese of San Juan de Cuyo (Latin: Archidioecesis Sancti Ioannis de Cuyo) is a Latin rite metropolitan diocese in Argentina. Its archiepiscopal seat is San Juan Cathedral (Spanish; Castilian: Catedral de San Juan Bautista), dedicated to Saint John the Baptist, in San Juan, Argentina. The city also has a minor basilica: the Spanish; Castilian: Basílica di Nuestra Señora de los Desamparados, or the Basilica of Our Lady of the Forsaken.
As per 2014, it pastorally served 638,183 Catholics (91.0% of 701,000 total) on 89,615 km² in 43 parishes and 216 missions with 96 priests (80 diocesan, 16 religious), 8 deacons, 85 lay religious (17 brothers, 68 sisters) and 21 seminarians.
The Metropolitan's suffragan sees are :