Biostrophin Explained

Biostrophin is a drug which may serve as a vehicle for gene therapy, in the treatment of Duchenne and Becker muscular dystrophy.[1]

As mutations in the gene which codes for the protein dystrophin is the underlying defect responsible for both disorders, biostrophin will deliver a genetically-engineered, functional copy of the gene at the molecular level to affected muscle cells.[1] Dosage, as well as a viable means for systemic release of the drug in patients, is currently being investigated with the use of both canine and primate animal models.[2]

Biostrophin is being manufactured by Asklepios BioPharmaceuticals, Inc., with funding provided by the Muscular Dystrophy Association.[3]

See also

Other drugs for Duchenne muscular dystrophy

External links

Notes and References

  1. 16391721 . Oct 2005 . Khurdayan VK, Bozzo J, Prous JR . Chronicles in drug discovery . 18 . 8 . 517–522 . 0214-0934 . Drug News & Perspectives . 10.1358/dnp.2005.18.8.953409.
  2. http://www.ncbiotech.org/news_and_events/industry_news/duchenne.html Dec 2006
  3. News: Asklepios Biopharmaceutical, Inc. Announces Cross License with GlaxoSmithKline. 2006-09-28.