Binaltorphimine Explained

Binaltorphimine (BNI) is a selective antagonist of the κ-opioid receptor (KOR).^[1] BNI and norbinaltorphimine (nor-BNI) were the first highly selective KOR antagonists to be discovered.

See also

• 5'-GNTI
• JDTic

Notes and References

1. Portoghese PS, Lipkowski AW, Takemori AE . Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists . Life Sci. . 40 . 13 . 1287–92 . March 1987 . 2882399 . 10.1016/0024-3205(87)90585-6.