| Bill Grahame | |
| Position: | Pitcher |
| Bats: | Unknown |
| Throws: | Left |
| Birth Date: | July 22, 1883 |
| Birth Place: | Owosso, Michigan, U.S. |
| Death Place: | Holt, Michigan, U.S. |
| Debutleague: | MLB |
| Debutdate: | April 18 |
| Debutyear: | 1908 |
| Debutteam: | St. Louis Browns |
| Finalleague: | MLB |
| Finaldate: | June 14 |
| Finalyear: | 1910 |
| Finalteam: | St. Louis Browns |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 14–29 |
| Stat3label: | Strikeouts |
| Stat3value: | 141 |
| Stat2label: | Earned run average |
| Stat2value: | 2.90 |
| Teams: |
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William James Grahame (July 22, 1884 – February 15, 1936), was a professional baseball player who played pitcher in the Major Leagues in -. He would play for the St. Louis Browns.