| Big Creek | |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Missouri |
| Subdivision Type3: | Region |
| Subdivision Name3: | Lincoln, St. Charles and Warren counties |
| Source1 Coordinates: | 38.7928°N -91.1517°W |
| Source1 Elevation: | NaNfeet |
| Mouth Coordinates: | 38.8789°N -90.8272°W |
| Mouth Elevation: | 433feet |
| Tributaries Left: | Schlanker Branch, Yeater Branch, Dry Creek, Coon Creek |
| Tributaries Right: | Hickory Lick Creek, Indian Camp Creek, McCoy Creek |
Big Creek is a stream in Lincoln, St. Charles and Warren counties of the U.S. state of Missouri. It is a tributary of the Cuivre River.
The source area for the stream lies just southwest of Warrenton in Warren County. The stream flows north passing under Interstate 70 and turns east passing under Missouri Route 47 before entering Lincoln county. The stream meanders east and becomes the boundary between Lincoln and St. Charles counties. It passes under US Route 61 and enters the Cuivre to the north of Wentzville, and the communities of Flint Hill and Enon.[1]
An early variant name was "Eagle Fork". According to tradition, the former name was applied because eagles often attacked an early settler's hogs.[2]