Bexlosteride Explained
Bexlosteride is a potent and noncompetitive inhibitor of the enzyme 5α-reductase related to finasteride and dutasteride.[1] [2] It is selective for the type I isoform of the enzyme.[1] It advanced to Phase III clinical trials, but development was halted at that stage, and it was never marketed.[3] [4]
See also
Notes and References
- Book: Chang C . Androgens and androgen receptor : mechanisms, functions, and clinical application . 2002 . Kluwer Academic Publishers . Boston . 1-4020-7188-4 .
- Book: Lednicer D . Strategies for Organic Drug Synthesis and Design . Wiley-Interscience . New York . 2008 . 978-0-470-19039-5 .
- Web site: Drug Profile: Bexlosteride. Adis Insight.
- [Reaxys]