Beta-phellandrene synthase (neryl-diphosphate-cyclizing) explained

β-phellandrene synthase (neryl-diphosphate-cyclizing)
Ec Number:	4.2.3.51

β-Phellandrene synthase (neryl-diphosphate-cyclizing) (EC 4.2.3.51, phellandrene synthase 1, PHS1, monoterpene synthase PHS1) is an enzyme with systematic name neryl-diphosphate diphosphate-lyase (cyclizing; beta-phellandrene-forming).^[1] This enzyme catalyses the following chemical reaction

neryl diphosphate

\rightleftharpoons β-phellandrene + diphosphate

The enzyme from Solanum lycopersicum has very poor affinity with geranyl diphosphate.

Notes and References

1. Schilmiller AL, Schauvinhold I, Larson M, Xu R, Charbonneau AL, Schmidt A, Wilkerson C, Last RL, Pichersky E . Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate . Proceedings of the National Academy of Sciences of the United States of America . 106 . 26 . 10865–70 . June 2009 . 19487664 . 2705607 . 10.1073/pnas.0904113106 . free .