Beta-apiosyl-beta-glucosidase explained

Beta-apiosyl-beta-glucosidase
Ec Number:	3.2.1.161

In enzymology, a beta-apiosyl-beta-glucosidase is an enzyme that catalyzes the chemical reaction

7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H₂O

\rightleftharpoons a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose

The 3 substrates of this enzyme are 7-[beta-D-apiofuranosyl-(1->6)-beta-D-], glucopyranosyloxyisoflavonoid]], and H₂O, whereas its two products are 7-hydroxyisoflavonoid and beta-D-apiofuranosyl-(1->6)-D-glucose.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase. Other names in common use include isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside], disaccharidase, isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase, and furcatin hydrolase.

References

• Hosel W, Barz W . 1975 . Beta-Glucosidases from Cicer arietinum L. Purification and Properties of isoflavone-7-O-glucoside-specific beta-glucosidases . Eur. J. Biochem. . 57 . 607 - 16 . 240725 . 10.1111/j.1432-1033.1975.tb02336.x . 2 . free .
• Cairns JR . 2005 . Purification of an isoflavonoid 7-O-beta-apiosyl-glucoside beta-glycosidase and its substrates from Dalbergia nigrescens Kurz . . 66 . 1880 - 9 . 16098548 . 10.1016/j.phytochem.2005.06.024 . Hua . Y . Svasti . J . Sakdarat . S . Sullivan . PA . Ketudat Cairns . JR . 16 .
• Ahn YO, Mizutani M, Saino H, Sakata K . 2004 . Furcatin hydrolase from Viburnum furcatum Blume is a novel disaccharide-specific acuminosidase in glycosyl hydrolase family 1 . J. Biol. Chem. . 279 . 23405 - 14 . 14976214 . 10.1074/jbc.M311379200 . 22 . free .