| Bernhard Sigmund Schultze | |
| Birth Date: | 29 December 1827 |
| Nationality: | German |
| Alma Mater: | University of Greifswald (doctorate) |
| Occupation: | Obstetrician, gynecologist |
| Employer: | University of Greifswald University Women's Hospital, Berlin University of Jena |
| Children: | Leonhard Schultze-Jena (son) |
| Relatives: | Max Schultze (brother) |
Bernhard Sigmund Schultze; sometimes spelled Bernhard Sigismund Schultze (29 December 1827 in Freiburg im Breisgau - 17 April 1919) was a German obstetrician and gynecologist. He was a younger brother to anatomist Max Schultze (1825–1874).
In 1851 he received his medical doctorate from the University of Greifswald, where in 1853 he became a lecturer on anatomy and physiology. During the following year, he became an assistant to Dietrich Wilhelm Heinrich Busch (1788–1858) at the University Women's Hospital in Berlin, and in 1858 relocated to the University of Jena as chair of the gynecological clinic. In 1864/65 he served as rector of the university.
His name is associated with an obstetrical term known as "Schultze's method", which is a resuscitation technique used on an apparent stillborn child. Other eponyms associated with Schultze include: