| Berne-Knox-Westerlo Junior-Senior High School | |
| Streetaddress: | 1738 Helderberg Trail |
| City: | Berne |
| State: | New York |
| County: | (Albany County) |
| Zipcode: | 12023 |
| Country: | USA |
| Coordinates: | 42.6269°N -74.1453°W |
| Schooltype: | high school |
| Fundingtype: | Public school (government funded) |
| District: | Berne-Knox-Westerlo Central School District |
| Superintendent: | Timothy Mundell[1] |
| Ceeb: | 330415 |
| Principal: | Mark Pitterson |
| Faculty: | 40.77 |
| Grades: | 6 - 12; Ungraded |
| Enrollment: | 327 |
| Enrollment As Of: | 2021-2022 school year |
| Grade6: | 47 |
| Grade7: | 52 |
| Grade8: | 69 |
| Grade9: | 69 |
| Grade10: | 65 |
| Grade11: | 47 |
| Grade12: | 46 |
| Other Grade Enrollment 1: | 7 |
| Other Grade Label 1: | Ungraded |
| Ratio: | 13.12 |
| Language: | English |
| Campus: | Rural: Distant |
| Colors: | Maroon and Gold |
| Mascot: | Bulldogs |
Berne-Knox-Westerlo Junior-Senior High School is a public high school located in Berne, Albany County, New York, U.S.A., and is the only high school operated by the Berne-Knox-Westerlo Central School District.