| Bernardo de Irigoyen | |
| Native Name Lang: | es |
| Settlement Type: | Town |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of Bernardo de Irigoyen in Argentina |
| Coordinates: | -32.1667°N -70°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Santa Fe |
| Subdivision Type2: | Department |
| Subdivision Name2: | San Jerónimo |
| Unit Pref: | Metric |
| Area Total Km2: | 284 |
| Population Total: | 1899 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | S2248 |
| Area Code Type: | Dialing code |
| Area Code: | +54 3466 |
Bernardo de Irigoyen is a town (comuna) in the center-east of the province of Santa Fe, Argentina. It has 1,899 inhabitants as per the . It is located 820NaN0 south-southwest from the provincial capital Santa Fe, on Provincial Route 10.
The town was founded in 1886, as the Buenos Aires–Tucumán railway reached the area. It was named after diplomat and politician Bernardo de Irigoyen, who donated lands for the town. It gained the official status of commune in 1923.
Bernardo de Irigoyen hosts an annual Bronc Riding and Folk Music Festival, in the second half of February, and celebrates the day of its patron, the Nativity of the Child Virgin Mary, on 8 September.