Berberonic acid explained

Berberonic acid (pyridine-2,4,5-tricarboxylic acid) is an organic compound that belongs to the heterocycles (more precisely the heteroaromatics). It belongs to the group of pyridinetricarboxylic acids and consists of a pyridine ring which carries three carboxy groups in the 2-, 4- and 5-positions. The name is derived from berberine.

Preparation

Berberonic acid is obtained in the oxidation of berberine with nitric acid.[1] It can also be derived by oxidative degradation of monascaminone with potassium permanganate.[2]

References

  1. Book: Wolffenstein, Richard . Die Pflanzenalkaloide . 1922 . 978-3-642-92449-1 . 3rd . Berlin, Heidelberg . 69–72 . de . 913710178.
  2. 10.1016/S0040-4020(01)99285-3. Structure of Monascorubrin. Tetrahedron. 18. 10. 1171–1184. 1962. Kumasaki. S.. Nakanishi. K.. Nishikawa. E.. Ohashi. M..