Benzylpenicilloyl polylysine explained

Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1] [2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3] [4] [5]

Notes and References

  1. Web site: Benzylpenicilloyl polylysine . PharmGKB.
  2. Web site: Benzylpenicilloyl polylysine . DrugBank .
  3. Vemuri P, Harris KE, Suh LA, Grammer LC . Preparation of benzylpenicilloyl-polylysine: a preliminary study . Allergy and Asthma Proceedings . 25 . 3 . 165–168 . 2004 . 15317320 . vanc .
  4. Goldschmidt BM, Levine BB . The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy . The Journal of Antibiotics . 36 . 6 . 709–714 . June 1983 . 6874593 . 10.7164/antibiotics.36.709 . free .
  5. Web site: PRE-PEN® (benzylpenicilloyl polylysine injection USP) Skin Test Antigen . DailyMed . U.S. National Library of Medicine .

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