Benzodioxolefentanyl Explained

Benzodioxolefentanyl should not be confused with Benzoylfentanyl.

Benzodioxolefentanyl is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug.^{[1] [2]}

Side effects

Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.^[3] A new wave of fentanyl analogues and associated deaths began in around 2014 in the US, and have continued to grow in prevalence; especially since 2016 these drugs have been responsible for hundreds of overdose deaths every week.^[4]

Legal status

In the United States, fentanyl-related substances are Schedule I controlled substances. Benzodioxolefentanyl was banned in Sweden in July 2017,^[5] and in Finland in September 2017.^[6]

See also

• Furanylfentanyl
• Cyclopentylfentanyl
• List of fentanyl analogues

Notes and References

1. https://www.policija.si/apps/nfl_response_web/0_Analytical_Reports_final/Benzodioxole-F-ID-1672-16-report.pdf European Project Response. Analytical Report Benzodioxole-F. National Forensic Laboratory, Slovenia. 14 September 2016
2. https://www.caymanchem.com/news/tips-for-interpreting-gc-ms-fragmentation-of-unknown-substituted-fentanyls Pierzynski HG. Tips for Interpreting GC-MS Fragmentation of Unknown Substituted Fentanyls. Cayman Chemical, 23 August 2017
3. Mounteney J, Giraudon I, Denissov G, Griffiths P . Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe . The International Journal on Drug Policy . 26 . 7 . 626–31 . July 2015 . 25976511 . 10.1016/j.drugpo.2015.04.003 .
4. Armenian P, Vo KT, Barr-Walker J, Lynch KL . Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review . Neuropharmacology . 134. Pt A. October 2017 . 121–132 . 29042317 . 10.1016/j.neuropharm.2017.10.016 . 21404877 .
5. https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2017/juli/tretton-nya-amnen-klassas-som-narkotika-eller-halsofarlig-vara/ The Public Health Agency of Sweden. Tretton nya ämnen klassas som narkotika eller hälsofarlig vara. 28 July 2017
6. http://ec.europa.eu/growth/tools-databases/tris/en/search/?trisaction=search.detail&year=2017&num=437 European Commission. Notification detail. Government Decree amending Annex IV to the Government Decree on substances, preparations and plants to be classified as narcotics The following 9 new substances are classified: 4-chloro-isobutyrfentanyl, 4-Fluoro-isobutyrfentanyl, 3-phenylpropanoylfentanyl, benzodioxole fentanyl, benzoyl fentanyl, cyclopentyl fentanyl, cyclopropyl fentanyl, methoxyacetyl fentanyl and tetramethylcyclopropyane fentanyl. 12 September 2017